' 
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
USERS' SCORE
Good
Based on 18 Reviews
8.7
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Acetyl-L-Carnitine (from Acetyl-L-Carnitine HCl)
1 g (1,000 mg)
**
Top Medical Research Studies
9
ALC improves motor function in MS
Ameliorative effects of acetyl-L-carnitine on corpus callosum and functional recovery in demyelinated mouse model.
Effectiveness score: high relevance
We examined the effects of acetyl L-carnitine (ALC) on motor function in mice with a demyelinating condition, simulating aspects of multiple sclerosis. In this study, some mice were treated with ALC while others were not, allowing us to compare their recovery.
The results were promising; ALC not only enhanced balance and motor coordination but also supported myelin repair by lowering oxidative stress. Key genes associated with myelin were positively regulated, indicating ALC's potential as a therapeutic agent in managing autoimmune disorders like MS.
The results were promising; ALC not only enhanced balance and motor coordination but also supported myelin repair by lowering oxidative stress. Key genes associated with myelin were positively regulated, indicating ALC's potential as a therapeutic agent in managing autoimmune disorders like MS.
Read More
9
ALCAR reduces apoptosis in neuropathy
Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy.
Significant relevance to autoimmune neuropathies
We examined how acetyl-L-carnitine (ALCAR) might help in cases of peripheral neuropathy linked to autoimmune conditions. In a controlled study involving rat subjects, we observed that ALCAR effectively reduced signs of nerve cell death, unlike other treatments.
By limiting apoptosis mechanisms—like the release of harmful proteins and the activation of cell death pathways—ALCAR showcased a protective effect. Overall, these findings suggest ALCAR could be a promising option for managing nerve damage related to autoimmune disorders.
By limiting apoptosis mechanisms—like the release of harmful proteins and the activation of cell death pathways—ALCAR showcased a protective effect. Overall, these findings suggest ALCAR could be a promising option for managing nerve damage related to autoimmune disorders.
Read More
8
ALCAR shows promise for MS fatigue
Comparison of the effects of acetyl L-carnitine and amantadine for the treatment of fatigue in multiple sclerosis: results of a pilot, randomised, double-blind, crossover trial.
Highly relevant findings confirmed
We examined the effects of acetyl L-carnitine (ALCAR) on fatigue in multiple sclerosis patients by conducting a randomized, double-blind, crossover trial with 36 participants. After comparing ALCAR with amantadine, a common fatigue treatment for MS, we found that ALCAR was significantly more effective in reducing fatigue severity.
While ALCAR showed better tolerance and positive results according to the Fatigue Severity Scale, secondary measures like the Fatigue Impact Scale and Beck Depression Inventory didn't indicate significant benefits. Overall, ALCAR may provide a valuable alternative for managing fatigue in MS patients.
While ALCAR showed better tolerance and positive results according to the Fatigue Severity Scale, secondary measures like the Fatigue Impact Scale and Beck Depression Inventory didn't indicate significant benefits. Overall, ALCAR may provide a valuable alternative for managing fatigue in MS patients.
Read More
Most Useful Reviews
9.5
Increased energy for recovery
I ordered carnitine for my 85-year-old mother, who had moderate COVID-19 and experienced heart complications and memory issues thereafter. After taking carnitine, her energy and endurance improved significantly, with stable blood pressure and mental clarity returning. We are very pleased with the results.
Read More
8.8
Improved brain function
I have been ordering for several years, 500 ml of 100 pills. This product from Now is perfectly balanced. The capsules are not large and white, and the composition helps my brain function more efficiently; my drowsiness has alleviated and my overall mood has improved. I highly recommend this high-quality product.
Read More
8.8
Improved normalcy
Acetyl-L-Carnitine was purchased for my dad to enhance his overall condition. Following a doctor's advice, he took 1 capsule twice daily. Initially, he was quite irritable and suffered from high blood pressure. However, after a month, his nerves settled, and his blood pressure returned to normal. His well-being improved significantly. We appreciated the quality, ingredients, and beneficial composition of the product.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.3
- All Researches
9
ALC improves motor function in MS
Ameliorative effects of acetyl-L-carnitine on corpus callosum and functional recovery in demyelinated mouse model.
Effectiveness score: high relevance
We examined the effects of acetyl L-carnitine (ALC) on motor function in mice with a demyelinating condition, simulating aspects of multiple sclerosis. In this study, some mice were treated with ALC while others were not, allowing us to compare their recovery.
The results were promising; ALC not only enhanced balance and motor coordination but also supported myelin repair by lowering oxidative stress. Key genes associated with myelin were positively regulated, indicating ALC's potential as a therapeutic agent in managing autoimmune disorders like MS.
The results were promising; ALC not only enhanced balance and motor coordination but also supported myelin repair by lowering oxidative stress. Key genes associated with myelin were positively regulated, indicating ALC's potential as a therapeutic agent in managing autoimmune disorders like MS.
Read More
9
ALCAR reduces apoptosis in neuropathy
Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy.
Significant relevance to autoimmune neuropathies
We examined how acetyl-L-carnitine (ALCAR) might help in cases of peripheral neuropathy linked to autoimmune conditions. In a controlled study involving rat subjects, we observed that ALCAR effectively reduced signs of nerve cell death, unlike other treatments.
By limiting apoptosis mechanisms—like the release of harmful proteins and the activation of cell death pathways—ALCAR showcased a protective effect. Overall, these findings suggest ALCAR could be a promising option for managing nerve damage related to autoimmune disorders.
By limiting apoptosis mechanisms—like the release of harmful proteins and the activation of cell death pathways—ALCAR showcased a protective effect. Overall, these findings suggest ALCAR could be a promising option for managing nerve damage related to autoimmune disorders.
Read More
8
ALCAR shows promise in MS therapy
The possible anti-apoptotic and antioxidant effects of acetyl l-carnitine as an add-on therapy on a relapsing-remitting model of experimental autoimmune encephalomyelitis in rats.
High relevance for MS research
We investigated how acetyl L-carnitine (ALCAR) could affect autoimmune disorders like multiple sclerosis (MS). In our study, we treated rats with relapsing-remitting experimental autoimmune encephalomyelitis using various approaches, including ALCAR alone and in combination with dexamethasone, a standard treatment.
The results showed that when combined with dexamethasone, ALCAR significantly reduced damaging compounds and boosted protective ones. This combination improved overall motor function and reduced harmful immune responses compared to untreated rats.
Thus, ALCAR appears promising as a supplementary treatment alongside traditional therapies for MS.
The results showed that when combined with dexamethasone, ALCAR significantly reduced damaging compounds and boosted protective ones. This combination improved overall motor function and reduced harmful immune responses compared to untreated rats.
Thus, ALCAR appears promising as a supplementary treatment alongside traditional therapies for MS.
Read More
8
ALCAR shows promise for MS fatigue
Comparison of the effects of acetyl L-carnitine and amantadine for the treatment of fatigue in multiple sclerosis: results of a pilot, randomised, double-blind, crossover trial.
Highly relevant findings confirmed
We examined the effects of acetyl L-carnitine (ALCAR) on fatigue in multiple sclerosis patients by conducting a randomized, double-blind, crossover trial with 36 participants. After comparing ALCAR with amantadine, a common fatigue treatment for MS, we found that ALCAR was significantly more effective in reducing fatigue severity.
While ALCAR showed better tolerance and positive results according to the Fatigue Severity Scale, secondary measures like the Fatigue Impact Scale and Beck Depression Inventory didn't indicate significant benefits. Overall, ALCAR may provide a valuable alternative for managing fatigue in MS patients.
While ALCAR showed better tolerance and positive results according to the Fatigue Severity Scale, secondary measures like the Fatigue Impact Scale and Beck Depression Inventory didn't indicate significant benefits. Overall, ALCAR may provide a valuable alternative for managing fatigue in MS patients.
Read More
7
Acetyl-L-carnitine delays diabetes onset
Children at risk of diabetes type 1. Treatment with acetyl-L-carnitine plus nicotinamide - case reports.
Study relevant for diabetes prevention
We explored the effects of acetyl-L-carnitine and nicotinamide on children at risk for type 1 diabetes. These children were carefully monitored over time, with some showing significant improvement in their diabetic markers after treatment.
Out of the nine participants, four experienced a return to normal parameters, while two continued treatment with positive outcomes. Unfortunately, one child did progress to diabetes after a delayed start. Overall, this treatment appears to delay or even reverse the development of type 1 diabetes in at-risk children.
Out of the nine participants, four experienced a return to normal parameters, while two continued treatment with positive outcomes. Unfortunately, one child did progress to diabetes after a delayed start. Overall, this treatment appears to delay or even reverse the development of type 1 diabetes in at-risk children.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Increased energy for recovery
I ordered carnitine for my 85-year-old mother, who had moderate COVID-19 and experienced heart complications and memory issues thereafter. After taking carnitine, her energy and endurance improved significantly, with stable blood pressure and mental clarity returning. We are very pleased with the results.
Read More
8.8
Improved brain function
I have been ordering for several years, 500 ml of 100 pills. This product from Now is perfectly balanced. The capsules are not large and white, and the composition helps my brain function more efficiently; my drowsiness has alleviated and my overall mood has improved. I highly recommend this high-quality product.
Read More
8.8
Improved normalcy
Acetyl-L-Carnitine was purchased for my dad to enhance his overall condition. Following a doctor's advice, he took 1 capsule twice daily. Initially, he was quite irritable and suffered from high blood pressure. However, after a month, his nerves settled, and his blood pressure returned to normal. His well-being improved significantly. We appreciated the quality, ingredients, and beneficial composition of the product.
Read More
9.5
Boosted energy levels
I’ve been feeling utterly exhausted for the past four months, even upon waking. I decided to try this supplement, and after just two weeks, I felt an immediate surge of energy. It truly revitalised me. If you find my review helpful, I’d appreciate a click on YES.
8.8
Enhanced memory retention
Acetyl-L-carnitine effectively reduces fat cells, lowering the risk of Alzheimer's and Parkinson's diseases. It strengthens memory and attention, especially helpful for those with memory disorders. This high-quality supplement is perfect for pre-training, providing a sense of energy and vitality.
Read More
